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differential rheumatology workup algorithm arthritis associations causes cholangitis dic disseminated injury interpretation intravascular laboratory lfts management primary rheumatoid rvalue table
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... but elevated as disease ... PBC Diagnosis ... #Cirrhosis #PBC ... #workup #hepatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... Anti-CCP, Rheumatoid ... cirrhosis (PBC) ... (TTG) - Celiac disease ... antibodies
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
, PBC, PSC, IgG4 ... stone, Malignancy, PBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... #chemistry #diagnosis ... #differential #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Disease: - Impaired ... hydration • RBC ... #diagnosis #causes ... treatment #management #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Diseases • Septic ... Complete blood count (CBC ... exclude inflammatory disease ... connective-tissue disease ... #Disease #Rheumatoid
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