6 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
(PBC) - Summary ... PBC Epidemiology ... 30-65 years PBC ... PBC Signs and ... • Fatigue PBC
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Dermatomyositis Anti-LKM (liver ... Primary biliary cirrhosis ... (PBC) Anticentromere ... diagnosis #table #rheumatology ... #antibodies
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
: < 1 • Cirrhosis ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... #transaminitis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... Disease: - Impaired ... HIT: Heparin-PF4 antibodies ... hydration • RBC ... treatment #management #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Complete blood count (CBC ... profile, including liver ... ferritin level, and iron ... diagnosis #testing #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Sarcoidosis) • Liver ... disease: Cirrhosis ... , PBC, PSC, Viral ... gastric tumors • Hematology ... differential #diagnosis #hematology