11 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... marrow failure with anemia ... #oncology #hematology ... #hemeonc #diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron ... Production #Index #hematology ... #diagnosis #calculation
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Spoon-shaped • Iron ... deficiency anemia ... discoloration) • Liver cirrhosis ... discoloration) • Chronic ... #Differential #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... rendering the immune system ... with no early symptoms ... • Neutropenia, anemia ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
count ↑ PLT • ↑ PBS ... all phases of maturation ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
primary biliary cirrhosis ... (PBC), or with ... : - Lymphocyte ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... : • T lymphocyte ... Signs and Symptoms ... #hepatology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
and Pathophysiology ... conditions) • Severe iron ... deficiency anemia ... - Obesity - Cirrhosis ... disorders - Chronic
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... Erythematosus #Diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
affected joint • Systemic ... the presence of anemia ... Screening Tests for Chronic ... ferritin level, and iron ... (to support a diagnosis