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management chronic cll differential lymphocytic aplastic cancer causes gastroenterology hemeonc hemochromatosis hepatology leukemoid leukocytosis mds myelodysplasia myelodysplastic syndromes thrombocytosis wbc
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Algorithm Features ... of hematologic ... hepatomegaly • Labs: anemia ... #Algorithm #hematology ... #WBC #Leukemoid
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... Artifact (redo CBC ... Chronic Myelogenous Leukemia ... malignancy • Iron ... deficiency anemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
count ↑ PLT • ↑ PBS ... all phases of maturation ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... marrow failure with anemia ... #oncology #hematology ... #hemeonc #diagnosis
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... suspected HH based on symptoms ... Patients with cirrhosis ... including liver and hematologic
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Lymphocytosis on CBC ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... • ↓ WBC • ↓ ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... • Hairy Cell Leukemia ... rings of excess iron ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
acute myeloid leukemia ... median age at diagnosis ... disease tolerate anemia ... toxicity from iron ... #algorithm #hematology
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