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differential disease management oncology agglutinin aplastic arthritis calculation dermatology erythematosus hemolytic hodgkins index infection laboratory legs lupus lymphoma microscopy morphology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... Bite Cell RBC: G6PD ... #RBC #Morphology ... #hematology #microscopy
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... deficiencies: Iron ... , Intrinsic RBC ... Production #Index #hematology ... #diagnosis #calculation
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Even with normal WBC ... relative to both WBC ... 21% had normal WBC ... #neutrophil #WBC ... #CBC #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... Blood smear - RBC ... disease #hemolytic #anemia ... #hematology #diagnosis
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
Cirrhosis w/recent ... Hippocrates in 5 BC ... as foot cellulitis ... hemochromatosis, hemolytic anemia ... #dermatology #legs
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Weight loss • Anemia ... Immune hemolytic anemia ... platelets - WBC ... #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... fibromyalgia) • Infections ... lymphopenia, low PLT • Anemia ... titers > 1:80 • CBC ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Complete blood count (CBC ... ferritin level, and iron ... #testing #Rheumatology
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