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management differential oncology chronic cll lymphocytic signs syndrome workup algorithm ana antibodies antinuclear bandemia behcet cancer causes cbc coagulation dic
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... primary biliary cirrhosis ... (PBC), or with ... like rheumatoid arthritis ... #Diagnosis #Signs
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... count ↑ PLT • ↑ PBS ... all phases of maturation ... #Hematology #Oncology ... #Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... meningitis), MCC CNS symptoms ... Behcet syndrome (Clinical ... tears, Ischemia, Leukemia ... #rheumatology #
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... chemotherapy for low-risk disease ... #oncology #hematology ... #hemeonc #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Primary Biliary Cirrhosis ... ANA #patterns #rheumatology ... #diagnosis #differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Lymphocytosis on CBC ... cells can indicate disease ... #oncology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Induced Lupus: • Symptoms ... Hodgkin lymphoma and leukemia ... #Rheumatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Tissue damage • Leukemia ... • Autoimmune diseases ... #CBC #hematology ... #pathophysiology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... ferritin level, and iron ... (to support a diagnosis ... ANA and RF (if clinical ... #testing #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... • Severe Liver Disease ... #Coagulation #diagnosis ... treatment #management #hematology
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