10 results
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Factor The maturation ... deficiencies: Iron ... #hematology #anemia ... #differential # ... diagnosis #calculation
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... substrate (e.g. iron ... OR reticulocyte index ... #Algorithm #Diagnosis ... #Workup #Hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... bile ducts Differential ... #diagnosis #workup ... #hepatology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework
LOW RETIC INDEX - ↓ PRODUCTION
 • Vitamin
in Cirrhosis - ... Differential Diagnosis ... Alcohol related, Iron ... #Cirrhosis #Differential ... #Diagnosis #Hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... deficiency, Other enzyme ... #workup #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
evaluation of the pattern ... BMI, body mass index ... ; FBC, full blood ... #Liver #Enzymes ... #Differential #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
value for this enzyme ... result in severe anemia ... from ischemia WBC ... count and differential ... #Workup #Hematology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... phlebotomy/ blood work ... procedures • Iron ... #differential # ... diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... ferritin level, and iron ... (to support a diagnosis ... #diagnosis #testing
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Liver disease: Cirrhosis ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential ... #diagnosis #hematology