11 results
diagnosis oncology algorithm hemolysis intravascular agglutinin classification disease leukemia monoclonal myelodysplasia myelodysplastic nonpalpable palpable paraproteinemias platelet purpura syndromes testing thromboticthrombocytopenicpurpura
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... purpura (TTP), ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Hemolysis - Differential ... anemia • ... • MAHA (TTP ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: ITP • Secondary ... /HUS - Hemolytic ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... • AIHA: warm, cold ... : TTP, HUS, DIC, ... #Anemia #Differential ... classification #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Agglutination - Cold ... - DIC, TTP, HELLP ... #Anemia #Differential ... #hematology #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential ... Diagnosis and Workup ... changes), high MCV anemia ... #Workup #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Secondary Cold ... anemia • Cold ... younger pts) Differential ... #anemia #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... for Thrombotic Thrombocytopenic ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... DDX: Rule Out Secondary ... Causes • Anemia ... blood count with differential ... Syndromes #diagnosis #hematology
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