19 results
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Algorithm Cl- ... , Gitelman syndrome ... the indicated causes ... the excretion of sodium ... #urine #Algorithm
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Diagnosis Algorithm ... anions • Renal tubular ... acidosis • Gitelman's ... syndrome • Bartter's ... #Causes #Classification
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... • Renal tubular ... acidosis (type ... #causes #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... distal convoluted tubule ... , Renal tubular ... acidosis (RTA))
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... diarrhea, Kidney tubular ... #causes #urinary
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... • Metabolic acidosis ... #causes #potassium ... #low #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... in the distal tubule ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology
Causes of Failure to Thrive - Differential Diagnosis Algorithm
Adequate Calorie Consumption
 - Increased Losses:
Causes of Failure ... • Renal Tubular ... Acidosis - Malabsorption ... Disorders • Syndromes ... #Causes #Peds #
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... tobacco, Renal tubular ... acidosis, Postobstructive ... #Causes #differential ... #diagnosis #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Hypovolemia, UNa ... with renal tubal acidosis ... Hypovolemia, UNa ... #Causes #nephrology