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differential msk workup approach comparison dermatology disease erythematosus rheumatoid sle syndrome systemic activation calcium classification cppd degenerative deposition fungal gout
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Pain History ... : Is the pain from ... trauma (e.g., meniscal ... #Pain #MSK #rheumatology ... #differential #diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... lesions • Discoid lupus ... #dermatology #joint ... #differential #diagnosis ... #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... with temporal arteritis ... Diffuse muscle pain ... #differential #diagnosis ... #comparison #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... pain / swelling ... #Rheumatoid #Arthritis ... #diagnosis #management ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... lesions Abdominal pain ... signs #symptoms #diagnosis ... #rheumatology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
nociceptors -> Pain ... in Rheumatoid arthritis ... , Lupus, etc) -> ... > Stiffness is short-lived ... JointDisease #JointPain #Diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... anterior chest wall, parts ... Diagnosis: ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... : • Joint pain ... arthropathy • 90% joints ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Fever is the main ... SJIA], systemic lupus ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
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