31 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
to Systemic Diseases ... Iron deficiency anemia ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #Diagnosis
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
an underlying systemic ... disease ... Syndrome • Leukonychia ... #differential #diagnosis ... #dermatology #nails
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
an underlying systemic ... disease ... Syndrome • Leukonychia ... #differential #diagnosis ... #dermatology #nails
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Demyelinating syndromes ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
- Differential Diagnosis ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... : • Systemic lupus ... #Hematology
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
Findings in or Near ... include diabetes, anemia ... seen in Reiter's syndrome ... #Pathology #Diagnosis ... #Clinical #Signs
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Petechial or purpuric rash ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... renal failure/uremia ... Myelodisplastic syndrome ... Psychiatric Disease ... #generalized #dermatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... - Hemolytic anemia ... autoantibodies #signs ... #differential #rheumatology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
includes Kawasaki disease ... and toxic shock syndrome ... erythematous rash ... #Diagnosis #Dermatology ... #Erythematous #Rash