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monoclonal differential gammopathy significance acute aki cancer chronic cll gammopathies gap globulin hodgkins injury kidney leukemia lymphocytic lymphoma management mds
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... No evidence of anemia ... insufficiency, Anemia ... #Significance #hematology ... #diagnosis #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... 40 ml/min A - Anemia ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
significance (MGRS ... • Hematologic ... #AKI #Cancer #Oncology ... #Differential #Diagnosis ... #Classification
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
patients with MGUS ... light-chain ratio Diagnostic ... Workup: • Kidney ... guide subtype classification ... #Significance #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Hodgkin Lymphoma Workup ... number of sites of disease ... #classification ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... cells can indicate disease ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Gammopathy Include: • MGUS ... Thalassemia, Sickle cell anemia ... #differential #diagnosis ... #hematology
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