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differential management chronic lymphocytic mds monoclonal myelodysplastic workup bandemia causes cbc cell classification gammopathy hemeonc hodgkins infections infectiousdiseases lymphoma mgus
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... organ or stem cell ... Scleroderma renal crisis ... anemia" • HELLP ... #hematology #hemolysis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... -> AML: Blast crises ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... • Neutropenia, anemia ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute leukemia ... Allogeneic stem cell ... Management #treatment #hematology ... #oncology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... iron deficiency, hemolysis ... Chronic myeloid leukemia ... (CML) - Dr. ... #Causes #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... 5) Symptoms of anemia ... uw_IMresidency #CLL ... #oncology #hematology ... #hemeonc #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... Tissue damage • Leukemia ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... No evidence of anemia ... insufficiency, Anemia ... to the plasma cell ... #diagnosis #oncology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic ... anemia (MAHA) ... Pathophysiology ... #rheumatology # ... nephrology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
count (anemia) ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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