9 results
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
liver failure ... Seizures Kidney ... Coagulopathy, Lactic acidosis ... Subclinical myocardial injury ... lung injury,
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... Liver Injury: ... HBV, HCV, HEV, EBV ... Liver Injury:
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Circulation Failure Kidney ... Injury (DILI) ... EmoryGastroHep #ACLF #Acute
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Skin involvement, Kidney ... non-essential drug/HDS treatments ... HBV, HCV, HEV, EBV ... dechallenge • Acute
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
paracentesis (>5 liter ... ) - 8g per liter ... ascites removed • Acute ... kidney injury ( ... Management #Cirrhosis #treatment
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... cycle found in the liver ... gastrointestinal distress and acute ... kidney injury are ... symptoms of metabolic acidosis
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... Treat underlying liver ... → No specific treatment ... #Kidney #Injury ... #treatment #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
or renal injury ... before beginning treatment ... cardiac output - Acute ... peritonitis - Acute ... Injury: • Reduced
#Visualabstract for the BICAR-ICU trial LANCET 

"Sodium bicarbonate therapy for patients with severe metabolic acidaemia in
patients with acute ... kidney injury. ... BICARICU #Acidemia #Acidosis ... VisualAbstract #EBM