22 results
Parkinson's Plus Syndromes - Atypical Parkinsonism
Main motor symptoms:
 • Tremors
 • Limb rigidity
 • Bradykinesia
Other symptoms
- Atypical Parkinsonism ... system atrophy (MSA ... parkinsonism • Vascular ... #Atypical #Parkinsonism ... #diagnosis #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
injury, often from vascular ... Upper extremity weakness ... anesthesia. leg weakness ... signs #symptoms #msk ... #orthopedics #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... differential #diagnosis #neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
of Peripheral Weakness ... No Objective Weakness ... Lambert-Eaton Myasthenic Syndrome ... #Peripheral #Weakness ... #Neurology #Differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... Lambert-Eaton - Isaacs' syndrome ... myopathies, the muscular ... Differential #Diagnosis #neurology
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
• Cauda Equina Syndrome ... claudication and weakness ... stopping walking (vascular ... Myotomes #diagnosis #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... ophthalmoplegia Atypical ... Spasm, Cramping, Weakness ... objective evidence of neurologic ... vision, Diplopia, Weakness
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
variable degree of weakness ... Limb- proximal weakness ... immunologic assay - MuSK ... Severe bulbar weakness ... diagnosis #management #neurology
Principal patterns of loss of sensation.
 (a) Thalamic lesion: sensory loss throughout opposite side (rare).
Brown—Séquard syndrome ... with ipsilateral weakness ... MS: loss of proprioception ... #Diagnosis #Neurology ... Review in Clinical Neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
- 85% have typical ... or respiratory weakness ... mild to moderate weakness ... or generalized weakness ... diagnosis #management #neurology