32 results
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
injury, often from vascular ... Upper extremity weakness ... anesthesia. leg weakness ... signs #symptoms #msk ... #orthopedics #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... differential #diagnosis #neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
of Peripheral Weakness ... No Objective Weakness ... Lambert-Eaton Myasthenic Syndrome ... #Peripheral #Weakness ... #Neurology #Differential
Parkinson's Plus Syndromes - Atypical Parkinsonism
Main motor symptoms:
 • Tremors
 • Limb rigidity
 • Bradykinesia
Other symptoms
Parkinson's Plus Syndromes ... Parkinson's plus syndrome ... system atrophy (MSA ... parkinsonism • Vascular ... Parkinsonism #diagnosis #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... Lambert-Eaton - Isaacs' syndrome ... myopathies, the muscular ... Differential #Diagnosis #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Miller Fisher Syndrome ... Guillain #Barre #Syndrome ... #diagnosis #management ... #treatment #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
variable degree of weakness ... Limb- proximal weakness ... immunologic assay - MuSK ... Gravis #diagnosis #management ... #neurology
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
• Cauda Equina Syndrome ... claudication and weakness ... stopping walking (vascular ... Myotomes #diagnosis #neurology
Primary and Secondary Headaches - Red Flags and Differential Diagnosis
Red Flags (SNOOP):
S - Systemic		
N - Neurologic
Systemic N - Neurologic ... Manipulation Vascular ... Amy Chung, MD, MSc ... primary #secondary #management ... #neurology
Principal patterns of loss of sensation.
 (a) Thalamic lesion: sensory loss throughout opposite side (rare).
Brown—Séquard syndrome ... with ipsilateral weakness ... MS: loss of proprioception ... #Diagnosis #Neurology ... Review in Clinical Neurology