9 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... dechallenge • Acute ... steatosis • Autoimmune ... #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... #Injury #Differential ... #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... , HBV, HCV, HEV, ... : Autoimmune hepatitis ... #injury #hepatitis ... #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... severe liver injury ... liver failure ... #HBV #Treatment ... Indications #management #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... Other: NAFLD, Autoimmune ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... subclinical disease to acute ... injury, though ... regarding need for treatment ... #Hepatitis #AIH
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... only increase short-term ... survival in severe AH ... can be bridge to Liver ... #treatment #hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... : - Acute kidney ... injury with serum ... #hepatology