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Inhibitors of Platelet Aggregation

#Antiplatelet #Inhibitors #Pharmacolgy #Pathophysiology #MechanismOfAction
Inhibitors of Platelet ... #Antiplatelet #Inhibitors ... Pathophysiology #MechanismOfAction
Mechanism of Action of Platelet Aggregation Inhibitors
- COX Inhibitors
- ADP Inhibitors
- GP IIb/IIIa Receptor Blockers

#Antiplatelet #Pharmacolgy
Platelet Aggregation Inhibitors ... - COX Inhibitors ... - ADP Inhibitors ... #Pharmacolgy #MechanismOfAction
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
Medications - Summary Table ... Aspirin - Inhibits ... in a-fib P2Y12 Inhibitors ... ticagrelor) - Inhibits ... Medications #Summary #Table
Summary of characteristics of Platelet Aggregation Inhibitors

#AntiPlatelet #Inhibitors #Pharmacology #Table #Overview #Interactions #Pharmacology #Cardiology
Platelet Aggregation Inhibitors ... #AntiPlatelet #Inhibitors ... #Pharmacology #Table
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... direct thrombin inhibitors ... Inhibitors: Non ... specific inhibitor ... Prolonged #Causes #diagnosis
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Summary table of ... Selective factor Xa inhibitors ... thrombin (factor lla) inhibitors ... doac #comparison #table
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Angiotensin-converting enzyme (ACE) inhibitors ... • Calcineurin Inhibitors ... #differential #diagnosis
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Direct Xa inhibitors ... Specific inhibitors ... Specific inhibitors ... Inhibitors ... Prolonged #Causes #diagnosis
Indications for and pharmacological properties of approved SGLT2 inhibitors

Canagliflozin - Dapagliflozin - Empagliflozin - Ertugliflozin

#SGLT2 #Inhibitors
approved SGLT2 inhibitors ... Ertugliflozin #SGLT2 #Inhibitors ... #pharmacology #table
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Medications Summary Table ... events TZDs DPP-4 inhibitors ... SGLT2 inhibitors ... #medications #table