14 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... fraction < 20% Differential ... abnormalities • Muscular ... diagnosis #management #treatment ... #rheumatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Diagnosis Neurologic-Centered ... Ig deposition disease ... #Diagnosis #hematology ... #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Medium and large ... ) Differential Diagnosis ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytes • Median ... immunophenotype Clinical ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Sneddon-Wilkinson disease ... #Monoclonal #Differential ... #Diagnosis #Oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... Reversible course Differential ... epilepticus Treatment ... underlying cause • Treatment
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease ... published cases, Median ... Relapsing-remitting course +++ Clinical ... IVIg) • Limit vascular ... #rheumatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
4) progressive muscular ... failure Diagnosis - Medical ... conditions listed in differential ... diagnosis column Treatment ... Lateral #Sclerosis #neurology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... joint and spine, & medium ... and lower jaw Treatment ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... pulse deficits vascular ... primary condition MEDIUM ... affects the skin, neurologic ... #Diagnosis #Rheumatology