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diagnosis causes algorithm high metabolic acidosis aniongap chloride intercellularshift low management nongap syndrome urinary
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... Hypocalciuria (spot urine ... #Hypokalemia
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... excretion • Acute ... renal failure • Chronic ... • Type 1 #Hyperkalemia ... #potassium #differential
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Before evaluating hypokalemia ... in evaluating hypokalemia ... @krithicism #Hypokalemia ... #potassium #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Bartter syndrome, Gitelman ... metabolic acidosis • Diabetic ... of sodium and potassium ... #Algorithm #nephrology ... #differential #
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Metabolic acidosis - Hyperkalemia ... cantaloupe #hyperkalemia
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Metabolic acidosis - Hyperkalemia ... images/12834 #hyperkalemia
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Ketoacidosis: Diabetic ... Hypokalemia ... Hyperkalemia ... Drug-induced hyperkalemia ... Potassium-sparing
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts: - Alkalosis ... (treatment of diabetic ... or induced) #Hypokalemia ... #Causes #differential
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... - Reduced Excretion ... nephron - TTKG > 7, Urine ... Creatinine • Chronic ... • NSAlDs #Hyperkalemia
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