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Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Differential Diagnosis ... • LDH ↑ • Hyperkalemia ... Hyperuricemia • Hyponatremia ... Diagnosis #Management ... #causes #treatment
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Hypokalemia ... Hyperkalemia ... Drug-induced hyperkalemia ... #diagnosis #causes
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Approach to Hypotonic Hyponatremia ... of hypotonic hyponatremia ... high or low Uosm ... Physiologic #Hypotonic #Hyponatremia ... diagnosis #table
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Differential Diagnosis ... Drugs (Statins), ... Monitor potassium ... Dialysis for severe hyperkalemia ... Diagnosis #Management
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Causing Hyperkalemia ... diagnosis #causes ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Causing Hyperkalemia ... diagnosis #causes ... #potassium #high
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
; High-Ceiling Diuretics ... nephrotic syndrome • Hyponatremia ... and euvolemic hyponatremia ... #Diuresis #Nephrology ... #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... of hyperkalemia ... #Hyperkalemia ... #Diagnosis #Management ... #Treatment #potassium