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Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Differential Diagnosis ... - Toxins - Drugs ... Hyperuricemia • Hyponatremia ... nephrotoxicity to kidney ... Monitor potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... reactions Common Drugs ... lysis syndrome - Rhabdomyolysis ... Medications 2. ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
and Management ... Drugs (Statins), ... Dermatomyositis) AKI ... Monitor potassium ... Dialysis for severe hyperkalemia
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... reactions Common Drugs ... lysis syndrome - Rhabdomyolysis ... Medications 2. ... #high #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Chronic progressive kidney ... Drug-induced hyperkalemia ... Potassium-sparing ... Metabolic #Acidosis #differential
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
diuresis can be high ... : Hypovolemia, Hypervolemia ... #differential # ... diagnosis #table ... #sodium #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Loop Diuretics; High-Ceiling ... • Hypercalcemia ... #Pharmacology #Medications ... #Table
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Loss of sodium/Potassium ... heat illness → Hypernatremia ... involvement: Muscles, Kidneys ... High body temperatures ... Hypocalcemia - Hyperkalemia
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... , RTA Type IV, AI ... Elimination (see Table ... #Treatment #potassium ... #nephrology #K