10 results
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Causes of Diffuse ... • Neoplastic (Leukemia ... , Lymphoma, Metastatic ... #Causes #Hematology ... #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Lymphadenopathy ... Diagnosis Algorithm ... #Diffuse #Lymphadenopathy ... #Oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... (NHL) ~60% - lymphadenopathy ... more diffuse, can ... Treated Like Acute Leukemias ... #Classification
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphoproliferative disorders ... • Richter’s Syndrome ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy
Malignancies
 - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms
Infections
 -
Diagnosis of Lymphadenopathy ... Kaposi sarcoma, leukemias ... , lymphomas, metastases ... venereum, primary and secondary ... arthritis, Sjögren syndrome
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
involved) • No leukemic ... translocation • Types: Classification ... disease: B symptoms, lymphadenopathy ... NonHodgkins #comparison #oncology ... #diagnosis #differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Presentation: • Lymphadenopathy ... Immunohistochemical studies (to differentiate ... #diagnosis #classification ... #hematology #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... pneumonitis • Diffuse ... activation and/or medications ... and leukemia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... DDX: Rule Out Secondary ... blood count with differential ... #diagnosis #hematology ... #oncology