11 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... , deficiency anemia ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... Diagnosis #Algorithm #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... Malignant tumors, Acute ... , Liver diseases ... key #diagnosis #differential ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Syndrome (CAS): ... symptoms - most common ... • Symptoms of anemia ... younger pts) Differential ... #anemia #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
, Acute blood loss ... : Alcohol use, Liver ... Myelodysplastic syndrome ... morphologic #mcv #differential ... diagnosis #causes #hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Anticoagulant Medications ... ) • Advanced Liver ... (VIII is most common ... Summary #table #comparison ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... deficiency • Liver ... - APLS • Acute ... #Diagnosis #hematology ... #rheumatology #
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases ... autoimmune hemolytic anemia ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... presents as an acute ... lymph node, or liver ... #treatment #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... von Willebrand syndrome ... defects in the common ... diseaseAcute ... #Diagnosis #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... common • Antihistone ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology