13 results
Megaloblastic Anemia vs Normal Peripheral Smear

#Megaloblastic #Anemia #Peripheral #Smear #Comparison #Clinical #Hypersegmented #Neutrophil
Megaloblastic Anemia ... Peripheral Smear #Megaloblastic
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
Megaloblastic neutrophils ... KyleBradleyMD #Megaloblastic
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
MCV > 100): • Megaloblastic ... antifolate) • Non-megaloblastic
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Macrocytic" • Megaloblastic ... deficiency • Non-megaloblastic
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
hemoglobinopathies, megaloblastic
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Hypochromia Megaloblastic
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
infiltration or megaloblastic
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
patients with severe/megaloblastic
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
• Macrocytic - Megaloblastic
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
will correct the megaloblastic