9 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
twitter.com/AmyChung #AntiCoagulation ... #Medications #Pharmacology ... Mechanisms #DOAC #Hematology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Anticoagulant #Anticoagulation ... #Loading #DVT #Pharmacology ... #Hematology
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Anticoagulants #DOACs #anticoagulation ... #Switching #hematology ... #pharmacology
Coagulation Cascade - Anticoagulant Targets
Here's the brief overview of where the main anticoagulants work on the
Here's the brief overview ... Anticoagulant #Targets #Anticoagulation ... #Pharmacology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
PCC (Kcentra) #anticoagulation ... #doac #noac #pharmacology ... #hematology #reversal
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... management #algorithm #pharmacology ... decisionaid #cardiology #hematology
Xa Inhibitors - Apixaban and Rivaroxaban 
Oral Xa inhibitors are recommended by CHEST as first-line for
Fibrillation requiring anticoagulation ... Here is an overview ... Rivaroxaban #Dosing #Pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Anticoagulant #Bridging #anticoagulation ... #pharmacology # ... management #hematology