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classification algorithm cryoglobulins dermpath granulomatosis lesions manifestations nonpalpable palpable pathology rash semiology signs skin types ulcers vasculitides
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Petechiae, Palpable purpura ... Urticarial/LCV) - Cryoglobulinemic ... - Microscopic polyangiitis ... : • Behcet Disease ... #dermatology #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... cryoglobulinemia ... #GPA #dermatology ... #rheumatology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
of Cutaneous Vasculitis ... correlations • Purpura ... (5%): PAN > GPA ... hemopathies (4%) • Cryoglobulinemia ... #dermatology #semiology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
carcinoma • Melanoma ... • Bleomycin Hematologic ... Thalessemia • Cryoglobulinemia ... #skinrash #dermatology ... #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /HSP • Cryoglobulinemia ... Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... Syndrome: • Clinical ... polyangiitis ... ) • Cutaneous ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• Microscopic Polyangiitis ... ANCA +MPO) • Cryoglobulinemic ... Low levels mixed cryoglobulinemia ... differential #diagnosis ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Differential Diagnosis ... / ANCA + MPO) Cryoglobulinemic ... (lower legs), cutaneous ... #Differential #Diagnosis ... #Rheumatology
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