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classification algorithm cryoglobulins dermpath granulomatosis lesions manifestations nonpalpable palpable pathology purpura rash semiology signs sjogrens syndrome types ulcers vasculitides
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
the Skin - Differential ... Urticarial/LCV) - Cryoglobulinemic ... - Microscopic polyangiitis ... : • Behcet Disease ... #dermatology #rheumatology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... • Bleomycin Hematologic ... Thalessemia • Cryoglobulinemia ... #skinrash #dermatology ... #causes
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... purpura • Mixed cryoglobulinemia ... #GPA #dermatology ... #rheumatology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
of Cutaneous Vasculitis ... Identification of causes ... (5%): PAN > GPA ... hemopathies (4%) • Cryoglobulinemia ... #dermatology #semiology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/HSP • Cryoglobulinemia ... - GPA - EGPA ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... Syndrome: • Clinical ... • Autoimmune diseases ... polyangiitis ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ANCA +MPO) • Cryoglobulinemic ... Vasculitis - Skin ... Low levels mixed cryoglobulinemia ... differential #diagnosis ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... / ANCA + MPO) Cryoglobulinemic ... #Differential #Diagnosis ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... : • 7%, Cryoglobulinemia ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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