10 results
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... Urticarial/LCV) - Cryoglobulinemic ... - Microscopic polyangiitis ... : • Behcet Disease ... #dermatology #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... purpura • Mixed cryoglobulinemia ... #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Skin Ulcers by Etiology ... • Bleomycin Hematologic ... Thalessemia • Cryoglobulinemia ... #skinrash #dermatology ... #causes
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
of Cutaneous Vasculitis ... Identification of causes ... (5%): PAN > GPA ... hemopathies (4%) • Cryoglobulinemia ... #dermatology #semiology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/HSP • Cryoglobulinemia ... - GPA - EGPA ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... Syndrome: • Clinical ... • Autoimmune diseases ... polyangiitis ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ANCA +MPO) • Cryoglobulinemic ... Vasculitis - Skin ... Low levels mixed cryoglobulinemia ... differential #diagnosis ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... / ANCA + MPO) Cryoglobulinemic ... #Differential #Diagnosis ... #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... : • 7%, Cryoglobulinemia ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... Muscle atrophy may cause ... had more severe disease ... #management #rheumatology ... #dermatology