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diagnosis algorithm classification cryoglobulins dermpath granulomatosis lesions manifestations nonpalpable palpable pathology polyangiitis purpura rash signs sjogrens skin skinrash syndrome types
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Dermatological semiology ... of Cutaneous Vasculitis ... (5%): PAN > GPA ... hemopathies (4%) • Cryoglobulinemia ... #dermatology #semiology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
the Skin - Differential ... Urticarial/LCV) - Cryoglobulinemic ... - GPA Cutaneous ... : • Behcet Disease ... #dermatology #rheumatology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
insufficiency • Vasculitis ... carcinoma • Melanoma ... • Bleomycin Hematologic ... Thalessemia • Cryoglobulinemia ... #skinrash #dermatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/HSP • Cryoglobulinemia ... - GPA - EGPA ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... purpura • Mixed cryoglobulinemia ... #dermatology #rash ... #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... Syndrome: • Clinical ... Cryoglobulinemia ... - GPA, EGPA, microscopic ... classification #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... arthralgia, arm/leg ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Nephrogenic DI Hematologic ... : • 7%, Cryoglobulinemia ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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