820 results
Pathogenesis of PLA2R-associated (primary) Membranous Nephropathy

Immune deposits  → Activate complement  → C5b-9 complex
PLA2R-associated (primary) Membranous ... PLA2R #primary #Membranous ... #Nephropathy #pathophysiology
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Uveitis • Mucus Membranes ... ReactiveArthritis #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
restricted to mucous membranes ... Manifestations #pathophysiology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Inflammation of pleural membranes ... RheumatoidArthritis #RA #pathophysiology
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
cell walls/cell membranes ... C5C9Deficiency #Complement #pathophysiology
Trypanosomiasis - Trypanosoma cruzi Life Cycle
1) Triatomine bug takes a blood meal (passes metacyclic trypomastigotes in
wound or mucosal membranes ... LifeCycle #diagnosis #pathophysiology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Vessels • Mucous membranes ... weeks #Scurvy #Pathophysiology ... #AscorbicAcid #Pathophysiology
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology
Oral Cavity Lesions in a patient with HIV/AIDS
White plaque
 - Pseudo-membranous candidiasis
 - Oral hairy leukoplakia
plaque - Pseudo-membranous
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
glomerulosclerosis - Membranous