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diagnosis rheumatology lupus disease druginduced erythematosus signs syndrome systemic treatment activation adultonset behcet comparison dil fungal infections infectiousdiseases laboratory macrophage
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
erythema nodosum (septal ... Oral aphthae : SLE ... : SLE, Reactive ... Arthritis, AS Treatment ... Syndrome #diagnosis #management
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Systemic Lupus (SLE ... Joints (90%): Aseptic ... of hip (rare), Arthritis ... erythematosus #signs #symptoms
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... , Arthritis, myalgia ... constitutional symptoms ... 40, F:M 9:1 • Clinical
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... erythematosus [SLE ... brucellosis) • Sepsis ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Fever, Arthralgia/arthritis ... Complications: MAS ... splenomegaly • Hepatic ... Disease #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Malignancy (e.g. hematologic ... lymphoproliferative syndrome Clinical ... , APLA, PAC • Aseptic ... Induced Lupus: • Symptoms
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic ... arthritis - Gram ... ANA and RF (if clinical ... diagnosis #testing #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Constitutional symptoms ... , Arthritis, myalgia ... is rare in DIL, SCLE-DIL ... diagnosis #treatment #management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... the most common clinical ... + Nonspecific symptoms ... : • SLE • RA - ... #diagnosis #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
five major clinical ... fungal stain of clinical ... • Meningitis, septic ... arthritis, and ... Fungal #Diagnosis #Management
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