9 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Disease Clinical ... Fever, Arthralgia/arthritis ... #Stills #Disease ... #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Disease (AOSD) ... BrighamChiefs #AdultOnset ... #Stills #Disease ... #AOSD #rheumatology ... #diagnosis #management
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Septic Arthritis ... Diagnosis and Management ... Summary Clinical ... ROM +/- fever, chills ... necrosis, Lyme disease
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... erythema nodosum (septal ... Behcet syndrome (Clinical ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... Fever is the main clinical ... brucellosis) • Sepsis ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... , adult-onset Still ... Non-autoimmune rheumatologic ... lymphoproliferative syndrome Clinical ... , APLA, PAC • Aseptic
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +, Adult-onset Still ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Subcutaneous dissecting hematoma ... • Severe Liver Disease ... causes #treatment #management ... #hematology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... fungal stain of clinical ... arthritis, and ... Fungal #Diagnosis #Management