11 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... thiazidic, PPI, ACE, calcium-b ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Summary • Epidemiology ... of SLE versus DIL ... life-threatening • Treatment ... #Summary #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... #AdultOnset #Stills ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Fever, Arthralgia/arthritis ... MAS, Visceral, DIC ... Disease #diagnosis #management ... #treatment #rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... thiazidic, PPI, ACE, calcium-b ... #DIL #rheumatology ... #diagnosis #treatment ... #management
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
Rheumatoid Arthritis ... Summary Overview ... exam and imaging Treatment ... #diagnosis #management ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Fibrinogen level, ↑ sIL ... +, Adult-onset Still ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pseudogout Summary ... - Calcium Pyrophosphate ... Acute Pseudogout: Treatment ... Deposition #Disease #Rheumatology ... #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... nonerosive inflammatory arthritis ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management