21 results
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
) Deposition Disease ... - Acute CPPD ... polyarticular arthritis ... #Disease #Signs ... #Symptoms #Pathophysiology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Disease: • Pain ... disease must be ... trauma (e.g., meniscal ... necrosis, and Paget disease ... #Pain #MSK #rheumatology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... diseases features ... Extra-articular signs ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
swelling in weird joints ... • Underlying disease ... states Pathophysiology ... inflammatory arthritis ... Inflammatory Arthritis
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... ) - MSK Radiology ... mass and NO prior signs ... (RA, CPPD) - Can ... diffuse chondral disease
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
crystals from joints ... and/or x-ray - CPPD ... warm, swollen joint ... #Disease #Signs ... #Symptoms #Pathophysiology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition Disease ... (CPPD) Pathophysiology ... swelling in weird joints ... metacarpophalangeal joints ... MCP or shoulder joints
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
of the Hip • Arthritis ... Chondrodysplasia Neurologic ... Trendelenburg #Gait #pathophysiology ... causes #symptoms #signs ... #diagnosis #msk
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
disease Inflammatory ... Joint Disease ... in Rheumatoid arthritis ... Comparison #Versus #MSK ... JointPain #Diagnosis #pathophysiology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Fever/Chills/Joint ... - Systemic disease ... SLE - Behcet Disease ... Ligamentous injuries - Meniscal ... differential #diagnosis #msk