9 results
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
Chondrocalcinosis: Calcium ... ) Deposition Disease ... polyarticular arthritis ... #Disease #Signs ... #Symptoms #Pathophysiology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Disease: • Pain ... disease must be ... dihydrate • Basic calcium ... trauma (e.g., meniscal ... #Pain #MSK #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pseudogout Summary - Calcium ... (CPPD) Pathophysiology ... swelling in weird joints ... metacarpophalangeal joints ... MCP or shoulder joints
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
> Clearance of calcium ... crystals from joints ... mineralization of calcium ... #Disease #Signs ... #Symptoms #Pathophysiology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
swelling in weird joints ... • Underlying disease ... states Pathophysiology ... precipitates with calcium ... inflammatory arthritis
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... ) - MSK Radiology ... mass and NO prior signs ... (RA, CPPD) - Can ... diffuse chondral disease
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
of the Hip • Arthritis ... Chondrodysplasia Neurologic ... Trendelenburg #Gait #pathophysiology ... causes #symptoms #signs ... #diagnosis #msk
Popliteal (Baker’s) Cyst: Pathogenesis and clinical findings
 • Idiopathic
 • Meniscal Lesions
 • Osteoarthritis
 • Rheumatoid
Idiopathic • Meniscal ... • Rheumatoid Arthritis ... Popliteal #BakersCyst #MSK ... #pathophysiology ... #signs #symptoms
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
nephrocalcinosis • CPPD ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... ALP -> PPi and Calcium ... respiratory failure • Neurologic