11 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... Reactive Syndrome ... injuries - Meniscal ... #msk #physicalexam
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Coxsackie, CMV, EBV, HIV ... hepatitis • Pulmonary ... : pleural effusion ... #treatment #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... 50%): Pleurisy / effusion ... Aseptic necrosis of hip ... Demyelinating syndromes ... #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... : • 10%-15% Pulmonary ... thickening or effusion ... phenomenon (16%) MSK ... #Rheumatology #
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
trauma (e.g., meniscal ... e.g., congenital hip ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... shunt (Type 2) Clinical ... scanning or pulmonary ... no established medical ... hepatopulmonary #syndrome
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
thrombophlebitis, pulmonary ... : • + Clinical ... • TTP, HUS and HIT ... Antiphospholipid syndrome ... #rheumatology #
Popliteal (Baker’s) Cyst: Pathogenesis and clinical findings
 • Idiopathic
 • Meniscal Lesions
 • Osteoarthritis
 • Rheumatoid
Pathogenesis and clinical ... Idiopathic • Meniscal ... intra-articular knee ... Popliteal #BakersCyst #MSK ... signs #symptoms #diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... presentations and disease ... output - Acute pulmonary ... - Compartment syndrome ... Ethylene glycol - HIV
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... noncompliance • Clinical ... initiation Clinical ... infiltrates, pleural effusions