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differential hematology management classification cold disorders druginduced endocarditis hemophagocytic hlh infective lupus lymphohistiocytosis marantic nbte noninfective pericarditis platelet presentation reactions
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Discontinuation of causal ... #comparison #table ... #rheumatology # ... diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... decreased PLT count: CBC ... pylori test (GI symptoms ... test, ANA (e.g., SLE ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... ARDS to explain symptoms ... #diagnosis #comparison ... #table
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... and duration of symptoms ... angioedema Other symptoms ... #rheumatology # ... comparison #table
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... treatment #summary #rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
associated with rheumatologic ... life-threatening causes ... #Pericarditis #Symptoms ... #Presentation #comparison ... #Table #Diagnosis
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 Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs/symptoms ... conditions: Autoimmune (SLE ... in up to 30% of cases ... #Endocarditis #comparison ... #table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Presentation - Systemic Symptoms ... Lab Tests: • CBC ... vasculitis, and SLE ... #rheumatology #
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