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differential hellp liver obstetrics pregnancy hepatitis leukemia table thrombocytopenia ttphus abnormal anemia aplastic chronic cll disease enzymes icp injury lfts
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
of Pregnancy (AFLP ... ) Three syndromes ... #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
necrosis HELLP Syndrome ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... #algorithm #hepatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... Constitutional Syndromes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... presence of metabolic syndrome ... ALP, alkaline phosphatase ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... just beneath the skin ... #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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