21 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Shock and Vasoactive ... Cardiogenic: Acute MI ... vasoactive drug pharmacology ... Vasoactive #Drugs #pharmacology ... diagnosis #management #comparison
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Pharmacology of ... Thiazide‐like diuretics, MRA ... #Diuretics #Pharmacology ... #Comparison #Table
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
: Distributive shock ... ), Cardiogenic shock ... , Shock where ↑ ... Vasopressors #Inotropes #comparison ... #table #pharmacology
IBS-C Pharmacotherapy

Polyethylene glycol
Lubiprostone
Linaclotide
Plecanatide
Tegaserod
Tenapanor

#IBSC #IBS #Constipation #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison
IBS-D Pharmacotherapy

Loperamide
Rifaximin
Eluxadoline
Alosetron
Antispasmodics
Tricyclic antidepressants
SSRIs

#IBSD #IBS #Diarrhea #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... in refractory shock ... in setting of shock ... criticalcare #summary #comparison ... #table #pharmacology
Bedside Classification of Shock

Hypovolemic shock 

- Vomiting, diarrhea, overdiuresis 

- Hemorrhage (GI, peritoneal, RP) 

Distributive shock
Classification of Shock ... Hypovolemic shock ... - Septic shock ... Endocarditis - Post-MI ... #Cardiogenic #Comparison
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
Undifferentiated Shock ... ), LV Failure (MI ... Valves (wide open MR ... CCB, BB, BRASH syndrome ... cytokine release syndrome
Vasopressors Demystified

Shock comes in many flavors and so do vasopressors. Here’s a OnePager summarizing my approach
Demystified Shock ... CriticalCare #Management #Pharmacology ... #Comparison #Inotropes
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... failure, acute MI ... anaphylaxis, release syndrome ... uw_IMresidency #Shock ... Diagnosis #table #comparison