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differential management disease hematology joint causes cppd msk rheumatoid syndrome workup activation ana antibodies antinuclear approach bone calcium comparison deposition
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
differentiated: • Inflammatory ... and many other inflammatory ... trauma (e.g., meniscal ... #MSK #rheumatology ... #differential #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Diagnosis Framework ... axial (spine, shoulders ... - Autoimmune Rheumatologic ... #Diagnosis #MSK ... #rheumatology #
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... : - Systemic Inflammatory ... • Rheumatoid Arthritis ... #Hematology #Oncology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... hands/feet, knees, shoulders ... ) • joint pain ... #Rheumatoid #Arthritis ... #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
of Bone/Joint Pain ... common sites: hip, shoulder ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis ... #causes #hematology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
weird joints (shoulders ... onset of swelling, pain ... Wrist, MCP, or shoulder ... swelling, significant pain ... Gout #Comparison #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... arthritis • Acne ... anterior chest wall, parts ... SAPHO #Syndrome #Rheumatology ... #Dermatology
Ear Pain (Otalgia) - Differential Diagnosis Framework Primary Otalgia - Pain that originates from the ear
- Differential Diagnosis ... • Melanoma Inflammatory ... should be considered ... vision or black spots ... #differential #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
release of pro-inflammatory ... • Fever is the main ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
weird joints (shoulders ... onset of swelling, pain ... Wrist, MCP or shoulder ... with acute neck pain ... Deposition #Disease #Rheumatology
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