11 results
diagnosis hematology treatment clinical hemophagocytic hlh injury latenttb lymphohistiocytosis msk tb tuberculosis behcet disease dislocation erythematosus hemeonc knee lupus macrophage
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Initial screening test ... monitor disease activity ... block • Sjogren syndrome ... Summary #diagnosis #rheumatology ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Liver function tests ... MAS #Macrophage #Activation ... #Management #Hematology ... #Rheumatology
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis infections/year ... • Endogenous reactivation ... Tuberculin skin test ... Inhibitor: • Risk of reactivation ... TB #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis infections/year ... • Endogenous reactivation ... Tuberculin skin test ... Inhibitor: • Risk of reactivation ... TB #Diagnosis #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Positive pathergy test ... is a skin prick test ... Giant retinal tears ... #diagnosis #management ... signs #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... excessive macrophage activation ... absent NK cell activity ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Symptomatic: artificial tears ... muscarinic agonists • Active ... #Rheumatology # ... Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... Syndrome) 3. ... absent NK-cell activity ... #Hematology #HemeOnc
Pectoralis Major Rupture Injury during Bench Press Exercise CLINICAL: a rare injury patterns with typical sudden "tear/pop"
typical sudden "tear ... immobilization, rest ... Muscle belly tears ... Inferior to operative management ... Injury #clinical #video
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 Posterior Knee Dislocation Injury Specifically, POSTERIOR KNEE DISLOCATIONS can have significant associated injury that needs unique approach
nerve injury (25%) TEST ... Compartment syndrome ... special ligament/meniscus ... >> LINK TO ACL TEARS ... msk #clinical #video
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