45 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Workup History ... plateletcount), peripheral blood ... testing - Lab ... #Causes #Workup ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... Like in this case ... #rheumatology # ... approach #workup
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... evaluation or workup ... 1,500 cells/µL Workup ... #Differential #diagnosis ... #hematology #eosinophilia
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... : HIV test, a rubella ... : • Complete blood ... #diagnosis #testing ... #Rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
trauma (e.g., meniscal ... e.g., congenital hip ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
: • 2 sets of blood ... the preferred test ... an accessible joint ... typically part of the workup ... for HIV, Chlamydia
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... common sites: hip ... #differential #diagnosis ... #causes #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Aseptic necrosis of hip ... pain (20%) Renal disease ... Glomerulonephritis Myositis(5%) Blood ... signs #symptoms #diagnosis ... #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Algorithm Normal Blood ... Liver Function Tests ... #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Positive Coombs testing ... Mycoplasma, EBV, HIV ... sensitize red blood ... test #cold # ... hemolytic #anemia #hematology