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ILD of Known Cause - Differential Diagnosis Exposure: • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis • Treatment Related:
ILD of Known Cause ... Related: Radiation, Methotrexate ... BrighamChiefs #ILD
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Lung Diseases (ILD ... Exposure-Related ILD ... ILD caused by inhalation ... Nitrofurantoin, Methotrexate ... ILD Secondary
RHEUMATOID LUNG DISEASE: • RA-associated interstitial lung disease (RA-ILD). • Pleural disease (pleural thickening/effusions). • Airway disease (Both upper & lower airway). • Rheumatoid
lung disease (RA-ILD ... toxicity (i.e., Methotrexate-induced ... function testing in ILD ... osteoporosis rather than ILD ... #ILD #RA #Rheumatoidlungdisease
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
Nitrofurantoin, Methotrexate ... Lung #Diseases #ILD
Immune Reactions and Immunosuppressant Drugs Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2 Muromonab-CD3 - Monoclonal antibody Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... cytokine synthesis - IL ... Basiliximab - IL ... Suppression of IL ... Azathioprine, Methotrexate
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation
Intrathecal (IT) methotrexate ... protection: • IT methotrexate ... mercaptopurine, Weekly oral methotrexate ... pneumonia, IT methotrexate ... L-Asparaginase, IT methotrexate
Candidates for Medical Treatment of Ectopic Pregnancy with Methotrexate - Hemodynamically stable - No
Pregnancy with Methotrexate ... examination #Methotrexate
Rheumatoid Arthritis - ACR 2021 Guidelines - Low Disease Activity - Moderate to High Disease Activity
Disease Activity - Methotrexate
Exposure Related ILD • Hypersensitivity pneumonitis • Pneumoconioses • Radiation pneumonitis • Medication-induced ILD Andrew Sanchez
Exposure Related ILD ... Medication-induced ILD ... Exposure #Related #ILD
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
CNI, ACEI/ARB, IL ... Atazanavir, Quinilones, Methotrexate
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