194 results
Methotrexate Renal Toxicity 
Prevention:
 • Alkalinize the urine, keep urine ph >7
 • Start pre-treatment 12
Methotrexate Renal ... Toxicity Prevention ... until levels of methotrexate ... @kdjhaveri #Methotrexate ... #Renal #Toxicity
Chemotherapy Toxicity Bear Mnemonic - Cumulatively Toxic Drugs and their Rescues
 • Asparagine: neurotoxicity
 • Cisplatin:
Chemotherapy Toxicity ... Demeclocycline) • Methotrexate ... #Chemotherapy #Toxicity
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
pyrimethamine and methotrexate ... toxicity.
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... evidence of marrow toxicity ... Kat_Watson #Methotrexate ... Antidote #Toxicology #Toxicity
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... Oral steroid, methotrexate ... Statin #muscle #toxicity
RHEUMATOID LUNG DISEASE:
•	RA-associated interstitial lung disease (RA-ILD).
•	Pleural disease (pleural thickening/effusions).
•	Airway disease (Both upper & lower airway).
•	Rheumatoid
Drug-induced lung toxicity ... (i.e., Methotrexate-induced
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Intrathecal (IT) methotrexate ... protection: • IT methotrexate ... mercaptopurine, Weekly oral methotrexate ... pneumonia, IT methotrexate ... L-Asparaginase, IT methotrexate
Candidates for Medical Treatment of Ectopic Pregnancy with Methotrexate 
 - Hemodynamically stable 
 - No
Pregnancy with Methotrexate ... examination #Methotrexate
Almost any type of cardiac arrhythmia is seen in digitalis toxic­ity. However, type II second-degree atrioventricular
seen in digitalis toxic­ity ... characteristic of digitalis toxicity ... changes in digitalis toxicity ... #ECG #Digoxin #Toxicity
Acetaminophen toxicity
Emergency Department Workup and Management - Rumack Matthew Nomogram

#Diagnosis #Management #Toxicology #APAP #Acetaminophen #Rumack #Nomogram
Acetaminophen toxicity ... Nomogram #Stages #Toxicity