9 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Diagnosis: • hemolytic ... younger pts) Differential ... #anemia #hematology ... #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
kg/day vs. 2.5 mg ... initiation • Differential ... Dexamethasone 10 mg ... q12h -> 10 mg q6h ... #management #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and autoimmune hemolytic ... than 100 to 300 mg ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
General Approach to Anemia - Differential Diagnosis Framework
1) Check reticulocyte count to determine if hypo/hyper-proliferative
2) Exclude
Approach to Anemia - Differential ... Diagnosis Framework ... hyper-proliferative 2) Exclude hemolysis ... ) 3) Use MCV & clinical ... #diagnosis #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... very remarkable w/differential ... per day or 1 mg ... them, but urgent rheumatology ... #Management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... nodosum • Immune hemolytic ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Syndrome (HES) - Diagnosis ... and Management ... than 1500 and clinical ... #eosinophilia #diagnosis ... #hematology #differential
Neurosarcoidosis - Diagnosis and Treatment
 • 5 to 40% of sarcoidosis, Heterogeneous, often inaugural
 • Central
neurosarcoidosis: Clinical ... , Exclusion of Differential ... Infliximab 3-5 mg ... #Treatment #management ... #neurology #rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... Prednisone at 1 mg ... Dermatomyositis #diagnosis ... #management #rheumatology ... #dermatology