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diagnosis differential management anemia reactions causes dermatology hepatology product rheumatology signs symptoms table transfusion treatment agglutinin algorithm alkaline alp arterial
Hemostasis Physiology The blood's response to blood vessel injury can be viewed as four interrelated steps. Roman
blood's response to blood ... numerals refer to coagulation ... #Hemostasis #Pathophysiology ... #Coagulation #Cascade ... #Hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic ... Microangiopathic hemolytic ... intravascular coagulation ... #anemia #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
= (Retic %) x (Hct ... long (in days) it ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... Platelet defects • Coagulation ... DIC/TTP/HUS - Hemolytic ... Kasabach-Merritt syndrome Coagulation ... necrosis) • VIT
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... ABO incompatible blood ... protein C and S Pathophysiology ... deficiency) • HIT ... treatment #management #hematology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
) -> Increased coagulation ... decreased anti-coagulation ... • Hematologic ... ) -> Increased blood ... Occlusion #CRAO #pathophysiology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
to 280 U/L • It ... bloodstream Hemolysis ... : • Hemolytic ... deficiency of red blood ... The presence of macro-LDH
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... Immunoglobulin M (IgM) • Blood ... Mycoplasma, EBV, HIV ... sensitize red blood ... #anemia #hematology
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
Blood Product Components ... Life Whole blood ... Hct 35%. 450mL blood ... proteins, all coagulation ... Contents #Volume #Hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... • Febrile Non-Hemolytic ... May have drop in Hct ... Extremely rare - HIV ... diagnosis #management #hematology
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