8 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Megaloblastic Anemia ... Schistocytes: Microangiopathic ... hemolytic anemia ... DIC, TTP, HUS) ... Smear #Analysis #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Diagnosis of TTP ... TMA: Thrombotic microangiopathy ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Mechanical Trauma (Microangiopathic ... hemolytic anemia ... thrombocytopenic purpura (TTP ... differential #diagnosis #hematology ... #anemia
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
microangiopathies (TMA) - TTP ... Drug-induced thrombotic microangiopathy ... macroangiopathic hemolytic anemia ... differential #diagnosis #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
The optimal TTR ... #management #algorithm ... #decisionaid #cardiology ... #hematology #warfarin
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
5) Symptoms of anemia ... Autoimmune cytopenias (ITP ... marrow failure with anemia ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
urinalysis 3) microangiopathic ... hemolytic anemia ... of arteries Management ... PLEX (overlap TTP ... Renal #Crisis #rheumatology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
cultures • 2D Echo TTE ... • TTE nondiagnostic ... Leukocytosis, anemia ... Endocarditis #diagnosis #management ... #cardiology