11 results
Differential Diagnosis of Anemias #Diagnosis #IM #Honc #Anemia #Differential #Iron #Algorithm #Microcytic #Macrocytic #Normocytic #Ddxof
#IM #Honc #Anemia ... #Differential # ... Iron #Algorithm ... #Microcytic #Macrocytic ... #Normocytic #Ddxof
Algorithm for the Evaluation of Anemia #Diagnosis #EM #IM #Honc #Anemia #Differential #Workup #Algorithm #Microcytic #Macrocytic
Diagnosis #EM #IM ... #Honc #Anemia # ... Differential #Workup ... #Algorithm #Microcytic ... #Ddxof
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Framework by MCV Microcytic ... inflammation) • Iron ... Folate deficiency, B12 ... aciduria, Drugs (e.g
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Under 80 = microcytic ... or B12 repletion ... of substrate (e.g ... . iron), low EPO ... Workup #Hematology #Microcytic
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
MCV - <80fL - "Microcytic ... " • Iron deficiency ... MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin B12 ... morphologic #mcv #differential
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... , Thalassemia, Iron ... RBC: Vitamin B12 ... Chemotherapy (e.g ... RBC #Morphology #differential
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Volume (MCV) - Differential ... Deficiency (Eg ... #Microcytic #Anemia ... #elevatedMCV #Differential
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
cardiomyopathy) • Folate - Macrocytic ... anemia • Vitamin ... B12 - Macrocytic ... Trace Minerals: • Iron ... nutrition #table #differential
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Increased Requirement (e.g ... - Low Serum B12 ... Liver Disease #Macrocytic ... #elevatedMCV #Differential
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
: • Worsening macrocytic ... anemia, yellow ... wt loss • If anemia ... - CBC, PBS - anemia ... , can consider IM