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Differential Diagnosis of Anemias #Diagnosis #IM #Honc #Anemia #Differential #Iron #Algorithm #Microcytic #Macrocytic #Normocytic #Ddxof
Anemias #Diagnosis #IM ... Iron #Algorithm #Microcytic ... #Macrocytic #Normocytic ... #Ddxof
Algorithm for the Evaluation of Anemia #Diagnosis #EM #IM #Honc #Anemia #Differential #Workup #Algorithm #Microcytic #Macrocytic
Diagnosis #EM #IM ... Workup #Algorithm #Microcytic ... #Macrocytic #Normocytic ... #Ddxof
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Under 80 = microcytic ... (EPO), iron or B12 ... of substrate (e.g ... Workup #Hematology #Microcytic ... #Macrocytic
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Framework by MCV Microcytic ... Infections Macrocytic ... Folate deficiency, B12 ... aciduria, Drugs (e.g
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Increased Requirement (e.g ... - Low Serum B12 ... - Low Serum B12 ... • Rule out B12 ... Liver Disease #Macrocytic
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... Etiology: • Vit B12 ... dietary intake (e.g ... : • Worsening macrocytic ... , can consider IM
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... anemia (sometimes) Macrocytic ... RBC: Vitamin B12 ... Chemotherapy (e.g
Differential Diagnosis of Hypoglycemia
Evaluation of Hypoglycemia
Patients with known diabetes who are not systemically ill and can
blood cultures - ECG ... Diagnosis #EM #IM ... #Hypoglycemic #Ddxof
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
- 0.4 mg IV/IM ... - 0.04 mg IV/IM ... dose: - 0.1 mg/kg ... patients - 0.001 mg/kg ... response after 10-12
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
monitor, telemetry, 12 ... -Lead EKG • Ensure ... Anaphylactic >> IM